Location: Mozambique// Organization: Delft Imaging

Introduction

The study investigates the prevalence of subclinical TB based on three case definitions and suggests implications for TB control in Mozambique.

Intervention
  • A nationwide cross-sectional, secondary analysis of data from a previously completed TB prevalence survey was used.
  • Adults (≥15 years) were screened for symptoms and underwent chest X-rays (CXR) with CAD4TB. Those who screened positive were asked to submit sputum samples.
  • Out of 70,114 individuals, 32,445 (74.9%) participated in the survey, 10,831 were eligible for sputum collection, and 121 had MTB detected. 89 were classified as survey TB cases.
Result
  • Among 89 survey TB cases, 59.5% had no persistent cough, 51.5% had no cough, and 43.8% had no TB suggestive symptoms.
  • TB was more frequent among male, individuals between 25 and 44 years old in urban settings. More than 80% of CXR show some abnormalities.
Conclusion
  • The study found a high prevalence of subclinical pulmonary TB in Mozambique and high TB burden countries.
  • The results suggest that TB may need to review the screening guidelines to identify subclinical cases effectively.

REFERENCE: Manhica, I. et al (2024, November 12-16). Prevalence of subclinical pulmonary TB in Mozambique: Implications for TB Screening [Presentation]. The Union World Conference on Lung Health, Bali, Indonesia.