Photo credit: Lisa Gerwing // Location: Uganda// Organization: DAHW

Introduction

The Uganda National TB and Leprosy Program adopted WHO’s recommendation to use digital X-rays with CAD for systematic TB screening. This study aims to determine the optimal CAD4TB threshold score to improve TB diagnostic yield.

Intervention
  • Twelve portable digital X-rays Delft Light with CAd4TB were deployed at health facilities and communities. Health workers were trained on X-ray use and the screening algorithm.
  • Sputum samples were collected from individuals with any CXR abnormalities for X-pert testing. Those confirmed with TB were started on standard TB treatment.
Conclusion
  • High TB diagnostic yield can be achieved with a CAD4TB threshold score of 50 or more, potentially saving X-pert tests.
  • The national TB program should strengthen sputum testing for individuals with a CAD4TB score of 50 or more and consider a lower threshold for PLHIV to improve TB case detection.

REFERENCE: Burua, A. et al (2024, November 12-15). Improving the diagnostic yield of TB from screening using digital X-ray fitted with computer-aided detection software: Lessons from programmatic implementation in Uganda [Poster Presentation]. The Union World Conference on Lung Health, Bali, Indonesia.